Summary
Rapid Growing Mycobacteria (RGM), or Non-Tuberculous Mycobacteria (NTM), are widely distributed in the environment and some of them are considered as emerging opportunistic pathogens. Nosocomial infections caused by RGM are usually difficult to treat as a consequence of the resistance to antibiotics or other external factors. Genomic approaches, together with the derived pan genome analysis of these microorganisms, are expected to open new insights to better understand the adaptation to different ecological niches, including the human body.
- Genome sequencing of significant environmental and clinical isolates of RGM, previously described1, in the M. abscessus/ M. chelonae/ M. immunogenum phylogenetic cluster, including representative type strains closely-related.
- Identification of gene families, functional characterization and comparative genomic analysis to describe the core- and pan- genome of RGM species.
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